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Objectives: The management of intractable epilepsy in children is a challenging problem.
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Neuromodulatory strategies are increasingly adopted for the treatment of intractable epilepsy in children.
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We describe three cases of successful functional hemispherotomy for intractable epilepsy in HHES.
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In children with intractable epilepsy that is refractory to medication, surgical treatment may be needed.
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Purpose: Brain malformations are a common cause of intractable epilepsy and cognitive dysfunction in children.
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Ketogenic diet is an established and effective non-pharmacologic treatment for drug-resistant epilepsy.
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Methods: We include patients with drug-resistant epilepsy onset before 18 years of age.
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Objective: Epilepsy surgery is the most effective treatment for select patients with drug-resistant epilepsy.
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Significance: Our study suggests that singleton WES is an effective diagnostic tool for drug-resistant epilepsy.
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Over time, he developed drug-resistant epilepsy associated with severe neurological regression and failure to thrive.
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Children with abnormal brain neuroimaging have a greater chance to develop pharmacoresistant epilepsy.
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Forty-four samples were harvested in patients who underwent resection for the treatment of pharmacoresistant epilepsy.
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One infant developed pharmacoresistant epilepsy.
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Methods: The authors studied 40 consecutive patients undergoing ATL for refractory epilepsy.
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OBJECTIVEAppropriately chosen candidates with medically refractory epilepsy may benefit from hemispheric disconnection.
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KD is effective against refractory epilepsy, but its precise mechanism is obscure.
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Possibility of MCDs should be considered during the evaluation of refractory epilepsy cases.
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Epilepsy surgery is a rewarding therapeutic alternative for patients with medically refractory epilepsy.
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Brain stimulation with low-frequency is emerging as an alternative treatment for refractory epilepsy.
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Medically refractory epilepsy is associated with significant morbidity and mortality.
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Methods: A total of 303 patients with refractory epilepsy after epilepsy surgery were included.
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Twenty-four patients with refractory epilepsy were treated with mexiletine as an additional antiepileptic drug.
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Lamotrigine is a newer antiepileptic drug useful as oral adjunctive therapy in refractory epilepsy.
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Psychiatric comorbidity is an important concern in patients with refractory epilepsy and may be undertreated.
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In our series, MTS was the most common finding in refractory epilepsy after CNS infections.
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Conclusion: Prolonged interictal EEG monitoring is mandatory in the successful management of patients with refractory epilepsy.
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Objective: Medically refractory epilepsy is amenable to neurosurgical intervention if the epileptogenic focus is accurately localized.
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We report one such case of PQD presenting with refractory epilepsy, which was diagnosed on MRI.
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Methods: In a prospective cohort study, patients with medically refractory epilepsy undergoing epilepsy surgery were recruited.
